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Listen Up!
The message is spreading. NEB has everything you need for your RNA-related workflows.
Highest capacity RNA cleanup of up to 3 mg per column using silica spin columns. Optimized for IVT RNA, modified nucleotides, and fast benchtop workflows.
High‑fidelity (~280× Taq) polymerase enables fast amplification of diverse targets up to 20 kb, with a hot-start setup, short extension times, and a 62°C universal annealing protocol.
This article traces molecular cloning’s history and progress, highlighting how improved enzymes, assembly methods, and DNA design tools have advanced cloning efficiency, precision and applications.
The NEBaseChanger® Primer Design Tool Tutorial video will explain how to design primers for site-directed and multi-site mutagenesis using NEBaseChanger. This tool is ideal for NEB Q5® and NEBuilder® HiFi DNA Assembly applications.
Read about how RNase 4 enables targeted isolation and LC-MS analysis of mRNA 5' cap structures, supporting accurate assessment of capping efficiency and mRNA critical quality attributes (CQAs).
The latest version of NEBaseChanger® is available to help design site-directed mutagenesis primers. Compatible with ambiguous bases, substitute based on amino acid position, batch upload for multiple primer sets and add mutations to primer tails.
Explore NEB Expressions, featuring a precision medicine case study from discovery to targeted therapy, cell-free dbDNA synthesis, enzymatic solutions for circular RNA enrichment, conservation efforts in Costa Rica, RNA workflow products and the 2026 Passion in Science Awards.
Accelerating RNA & DNA Therapeutics with Cell-free DNA Synthesis
Featured Webinar
Accelerating RNA & DNA Therapeutics with Cell-free DNA Synthesis
Learn about cell-free DNA synthesis for RNA and DNA therapeutics with a focus on closed-ended DNA inputs and an overview of the recent launch of our new EnClose™ Cell-free dbDNA Synthesis Kit.
RNase III Protocol Modification Can Enable Safe dsRNA Removal from IVT Samples
Posted on Monday, July 20, 2026
By
Iris Martinez, Illustrations by Tasha José
High-quality and pure RNA is a requirement for RNA therapeutics to avoid unwanted immune responses, not just a “nice to have.” In vitro transcription can be optimized, but additional cleanup may be needed. Enzymatic removal of dsRNA using RNase III preserves ssRNA integrity when refined using a protocol developed by NEB scientists.
Cell-free Protein Synthesis Enables Rapid Single-chain Fragment Production and Analysis
Posted on Thursday, July 9, 2026
By
Iris Martinez, Illustrations by Tasha José
Cell-free protein synthesis (CFPS) workflows allow for fast, scalable and cost-effective single-chain antibody fragment production. NEB scientists have outlined approaches to quickly and efficiently screen the discovery and initial characterization of novel antibody fragments with CFPS.
Growing Plants on the Moon: Plants for Space (P4S) Aims to Transform Food Sustainability in Space and on Earth
Posted on Monday, June 8, 2026
By
Iris Martinez, Illustrations by Tasha José
The Australian Research Council (ARC) Centre of Excellence in Plants for Space (P4S) is a consortium of international research partners working toward a future where plants support off-Earth habitation and on-Earth sustainability through the production of food, medicine and other materials. In this blog post, research fellow Dr. Marta Peirats-Llobet talks about P4S and the consortium's LEAF project which, in collaboration with NASA, aims to study the impact of the lunar environment on plant growth in a growth chamber.
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